Their first week of high school. The biggest party of the year. Mistakes will be made as four teenage boys navigate a night of mayhem and debauchery.

After he and his first wife separate, journalist David Sheff struggles to help their teenage son, who goes from experimenting with drugs to becoming devastatingly addicted to methamphetamine.

A tight-knit team of FBI investigators, along with their District Attorney supervisor, is suddenly torn apart when they discover that one of their own teenage daughters has been brutally murdered.